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| Modelo | Desplazamiento | Cil/Vál | kW/CV | Fuel | Producido | ||
| CLS 350 (218.359) | 3498 | 3498 Gasolina |
6 / 4 | 225 / 306 | 306 | Gasolina | 2011 - a.m. |
| CLS 400 (218.365) | 2996 | 2996 Gasolina |
6 / 4 | 245 / 333 | 333 | Gasolina | 2014 - a.m. |
| CLS 400 4-matic (218.367) | 2996 | 2996 Gasolina |
6 / 4 | 245 / 333 | 333 | Gasolina | 2014 - a.m. |
| CLS 550 (218.373) | 4663 | 4663 Gasolina |
8 / 4 | 300 / 408 | 408 | Gasolina | 2011 - a.m. |
| CLS 500 (218.373) | 4663 | 4663 Gasolina |
8 / 4 | 300 / 408 | 408 | Gasolina | 2011 - a.m. |
| CLS 550 (218.391) | 4663 | 4663 Gasolina |
8 / 4 | 300 / 408 | 408 | Gasolina | 2011 - a.m. |
| CLS 500 4-matic (218.391) | 4663 | 4663 Gasolina |
8 / 4 | 300 / 408 | 408 | Gasolina | 2011 - a.m. |
| CLS 550 | 4663 | 4663 Gasolina |
8 / 4 | 320 / 435 | 435 | Gasolina | 2011 - a.m. |
| CLS 550 4-matic | 4663 | 4663 Gasolina |
8 / 4 | 320 / 435 | 435 | Gasolina | 2011 - a.m. |
| CLS 63 AMG | 5461 | 5461 Gasolina |
8 / 4 | 399 / 543 | 543 | Gasolina | 2011 - a.m. |
| CLS 63 AMG (218.374) | 5461 | 5461 Gasolina |
8 / 4 | 410 / 558 | 558 | Gasolina | 2011 - a.m. |
| CLS 63 AMG (218.375) | 5461 | 5461 Gasolina |
8 / 4 | 430 / 585 | 585 | Gasolina | 2013 - a.m. |
| CLS 63 AMG S (218.376) | 5461 | 5461 Gasolina |
8 / 4 | 430 / 585 | 585 | Gasolina | 2013 - a.m. |
| CLS 63 AMG 4-matic (218.376) | 5461 | 5461 Gasolina |
8 / 4 | 430 / 585 | 585 | Gasolina | 2013 - a.m. |