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| Modelo | Desplazamiento | Cil/Vál | kW/CV | Fuel | Producido | ||
| ML 350 4-matic (164.186) | 3498 | 3498 Gasolina |
6 / 4 | 200 / 272 | 272 | Gasolina | 2005 - a.m. |
| ML 450 Hybrid 4-matic | 3498 | 3498 Gasolina/eléctrico |
6 / 4 | 200 / 272 | 272 | Gasolina/eléctrico | 2009 - 2011 |
| ML 500 4-matic | 4966 | 4966 Gasolina |
8 / 3 | 218 / 296 | 296 | Gasolina | 2005 - 2006 |
| ML 500 4-matic (164.175) | 4966 | 4966 Gasolina |
8 / 3 | 225 / 306 | 306 | Gasolina | 2005 - a.m. |
| ML 550 (164.172) | 5461 | 5461 Gasolina |
8 / 4 | 285 / 388 | 388 | Gasolina | 2007 - a.m. |
| ML 500 4-matic (164.172) | 5461 | 5461 Gasolina |
8 / 4 | 285 / 388 | 388 | Gasolina | 2007 - a.m. |
| ML 63 AMG 4-matic (164.177) | 6208 | 6208 Gasolina |
8 / 4 | 375 / 510 | 510 | Gasolina | 2006 - a.m. |
| ML 320 CDI 4-matic | 2987 | 2987 Gasóleo |
6 / 4 | 160 / 218 | 218 | Gasóleo | 2006 - 2008 |
| ML 320 CDI 4-matic (164.122) | 2987 | 2987 Gasóleo |
6 / 4 | 165 / 224 | 224 | Gasóleo | 2005 - 2009 |
| ML 350 CDI 4-matic | 2987 | 2987 Gasóleo |
6 / 4 | 155 / 211 | 211 | Gasóleo | 2009 - a.m. |
| ML 350 CDI 4-matic | 2987 | 2987 Gasóleo |
6 / 4 | 157 / 214 | 214 | Gasóleo | 2009 - 2010 |
| ML 350 CDI 4-matic | 2987 | 2987 Gasóleo |
6 / 4 | 190 / 258 | 258 | Gasóleo | 2010 - 2011 |